Q. I have been suffering for 4 years from La Peyronie's disease, I kindly asked your parrot about the treatment plaque, the cost of this intervention and whether it solves the problem.
A. Plastic thinking is quite complex, as there are various techniques that are chosen based on the experience of the treating physician, whether or not to reduce thought, to the general conditions of the patient (there are interventions that presuppose a longer duration with greater commitment anesthesiologic, for example) and so on. Also for prices, therefore, a technique that engages an operating room (operator, assistant, anesthesiologist, ferrist, external nursing assistant and dc) for longer, apparently longer. The results are also to be considered in a wider context: the age of the disease, the degree of compromise of the cavernous bodies, the age of the patient, any other illnesses already suffering from the patient, medications taken for surgical therapy, any allergies, etc. , the intervention does not rule out any repetitions in subsequent years.
Q. After a severe penis recurrence I already had 2 chirurgic interventions for straightening. Now a distance of years from the 1st intervention I noticed a new episode of modest dorsal incurvation. I would like to ask if it is the case to come back to intervention.
A. The disease is due to the loss of elasticity of the cladding bodies that make up the pens. For this reason, surgery can straighten out the mind but not fight the inflammatory process that causes the disease of cervical body cladding. As for a third intervention, this can possibly be decided by the physician from whom it has been operated twice already. Medical treatment may be appropriate, even if the treating physician recommends the third intervention, so as to avoid a curative recovery. The disease, in fact, is extensive and the intervention is not "medical" but mechanically straightens the penis while the disease continues its course.
Q. I would like to ask if the use of pentossifillin (Trental) in IPP therapy and intake methods is appropriate.
A. Pentossiphilin (Trental), Verapamil-like antifibrous drug (Isoptin) has been shown to have greater efficacy and speed in curing IPP disease. This does not mean that it must always be associated with specific antioxidant substances (propolis, blackberry, ginkgo biloba, silimarine, vitamin E) for complete therapy. Pentoxifylline can be taken by mouth (with some problems of gastric and intestinal side effects), by infiltration through intraplacal injections, or by transdermal delivery with a special hydrophoretic apparatus (Idrobrea®).
Q. Can I alternate the isoptin and trental application with ionic / hydrophoresis or should I first do a cycle with a medicine and then a cycle with another medicine?
A. There are no valid scientific studies that can answer the question. It can be said, however, that hydrophoresis with Trental is proving to be very effective, more than ionophoresis, which has already given much satisfaction.
Q: Is the Tendisulfur strong that utility can have?
A. There are no studies published in industry journals showing some validity of Tendisulfur.
Q. Now starting with ionophoresis after so many applications will I have to resign if I do not see any results?
A. We do not know the cause of the disease at this time, although there are suggestive hypotheses. We know, of course, that he is chronic, evolutive, benign, and only invalidates sexual activity with all that follows (psychological problems, couples, etc.). What we know about therapies also comes from the "field" experience. That is to say, tests have been carried out and in the end the treatments have been selected that have achieved the best results. We know that there is an inflammatory disease under the IPP, but we do not know what causes it. In this sense, almost all therapies are based on anti-inflammatory, antioxidant, and so on. Another assurance that we have acquired is that therapies made up of several substances administered by mouth and locally show absolutely better results than single-agent therapies. The therapies, validated by the studies, ensure the stabilization of the disease and its regression in percentages and various measures that we can never predict at the beginning of therapy. Surely the times are long.
Q. Applying daily during Rilastil cream massage can be helpful?
A. As far as you know, Rilastil has no ability to penetrate beyond the epidermis, so you do not see the usefulness of such a treatment. Unless there are any studies in this matter that are ignored and demonstrate deeper penetration of Rilastil. Ultrasound response and possibly cure Q. If the ultrasound shows a hyperecogenic area compatible with partial fibrosis of the cavernous body caused by trauma, can I exclude an IPP? A. If ultrasound shows a fibrotic area, no primary (IPP) or secondary (etiology) is important. We have to cure fibrosis.
Q. I noticed a sudden curvature of the penis, I notice a small cord in the distal part of the penis; what therapy to undertake?
A. From the therapeutic point of view, the best results are obtained with the polyterapies, possibly administered os and locally. Recent studies all Italians demonstrate the efficacy of some substances that have been tested in double blind, etc., ie according to the most stringent scientific criteria. The therapeutic pattern derived from these studies is as follows: Propolberry 3 P 1 cpr per day (this is a combination of propyl galaxin and bilberry anthocyanosides.) This combination was evaluated by the pharmacology institute of the University of Florence and defined as active, Siligin 2 cpr per day (association Silimarina with Ginkgo Biloba), Vitamin E, 300/400 mg daily (Serious studies demonstrate paradoxically that Vit. E alone is not effective on IPP or Fibrosis while acting as a catalyst for the substances described above), Hydrophoresis with Pentoxifylline, at least three to four times a week with a special device (Idrobrea®) or intraplacal infiltration (2 times per month).
Q. For about 18 months I am undergoing treatment for a Fibrosis in the penis, the andrologist has prescribed Vit. E 600mg, 2 capsules of Blueberry per day; I replaced it with Prolpolberry 3P 1 cpr at 8 months; From the ultrasound examination the 15mm plaque has decreased to 10mm. Can I continue taking Propolberry for another 8 months?
A. Therapy should be continued until complete disease stabilization. Stabilization can be: complete (disappearance of the plaque), partial (plaque reduction) nothing (block plaque to the status quo) .Propolberry 3P is currently the only product that has been effective (along with other substances) in double blind studies controlled and published.
Q. I was diagnosed, after severe pain in the penis, a dorsal IPP plaque below the throat. After the diagnosis I was subjected to two cycles of extracorporeal lithotripsy with shock waves (aimed at 'disintegrating' the fibrotic plaque). At the end of the cycle the pain in the penis has passed but the curvature (which is fortunately light) has remained and, to the touch, I still feel the plaque. The functionality of the penis has remained intact, apart from occasional and slight side effects in the affected area during both urination and ejaculation. Should the litotrissia sessions continue?
R. The ESWL (Litotrissia extracorporea) did not give particular and convincing results, however, as the disease is chronic, as chronic it must be therapy and, as we know, ESWL can not be applied daily or at least three times a week. Recent studies have shown that they have no effect on plaque reduction but only on (possibly) pain; for pain you can take an analgesic tablet.