In recent years, a therapeutic pathway has been identified that has produced good results, using a substance cocktail (Multiday Therapy): Propolberry 3P 1 cpr. Per day (this is the combination of two substances, Propoli and Cranberry in high doses, administered via a single tablet), Siligin 2 cpr per day (union between Silimarina, extracted from Cardio Mariano, and Ginkgo Biloba), Vitamin E 300/400 mg per day, Pancoxifillin Vial. The latter can be administered by intracavernosa periplacca injection; However, this practice can not be performed frequently (up to 2 times a month) for any reason: logistic problems (post - injection surgery), possible pains, continuous microtraums that could cause the paradoxical effect of a constant inflammation. To eliminate this, the transdermal drug may be introduced via specific electrical currents (Hydrophoresis). This mode must be carried out with a special electrode, patented by BREA, by the Idrobrea® device, which has been specially designed for penis hydrophoresis and which guarantees the diffusion of the substance across the surface of albuginee tunics. This electrode is the only one dedicated exclusively to penis hydrophoresis for the disease of Induratio Penis Plastica. Hydrophoresis must be carried out at least three or more times a week. The use of Pentossifilline instead of Verapamil, adopted for many years, is due to the greater power and rapidity in plaque stabilization and subsequent reduction of the plate, resulting in the straightening of the penstock.  Care needs to be extended as there is no treatment to date that guarantees the definitive healing. The above mentioned therapy (coming from large-scale clinical trials in Italy and receiving the consensus of the major andrologist specialists) ensures the stabilization of the disease, ie the fact that the disease does not deteriorate since the IPP, if left alone Itself, tends to get worse, or in the event of suspension of the therapy, to recur. They can wait for improvements after 6 to 6 months of THERAPY. In short, today's medical treatment that has given the brightest results at a faster rate is:

Injection or transdermal injection of Pentosyphillin (with a special IdroBrea® hydrophoric apparatus)

Vitamin E (at least 300mg / die)

Propolberry 3P (Propoli 600mg, Cranberry 160mg) 1 cpr / die

Siligin (Silimarina 400mg, Ginkgo Biloba 250mg) 2 cpr / die

Dolaut gel (Diclofenac sodium) 1/2 application / day